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By implementing standardized methodologies and normalized research practices, the modernization and internationalization of Chinese medicine will be better supported, facilitating its broader acceptance and application worldwide
Future GLP-2 trials in IBD should stratify patients by disease phenotype (mucosal UC, inflammatory CD, stricturing CD) and incorporate serial cross-sectional imaging to monitor for stricture progression, given the mechanistic link between GLP-2R signaling through subepithelial myofibroblasts and intestinal fibrogenesis
At higher doses, some people experienced more intense digestive side effects, and in a larger phase 3 trial, about 12 to 18% of people stopped treatment because of side effects
And the washout period between stopping one and starting the other remains one of the most misunderstood aspects of the entire process
Three of the studies did not detect the products of oxidative metabolism following therapeutic dosing in children [44, 46, 48]
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